Increased serum ranges of tumor necrosis factor alpha precede major complications of bone marrow transplantation. Hepatic veno-occlusive illness after bone marrow transplantation. Serum levels of cytokines after bone marrow transplantation: elevated IL-8 ranges during severe veno-occlusive illness of the liver. A popular clinical use for NAC is as a treatment for acute liver toxicity as a consequence of acetaminophen poisoning. People suffering from chronic respiratory circumstances can also benefit from common use of N-A-C.